Multi-component Reactions Based on Formal [2+2] Reaction of Benzyne with Formamide

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REACTIONS OF DIHYDROPYRIDINES WITH BENZYNE

Reactions of 1 ,Zdihydropyridines (la-c) and 1,4-dihydropyridines (2a-c) in the presence of benzyne (3) under thermal conditions, and in the case of (2c) under photochemical conditions, have been investigated. Benzyne acts as an oxidizing agent to convert dihydropyridine (la) and (2a) to the corresponding pyridine (4) or adds as a dienophile to (lb-c).

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15 صفحه اول

reactions of dihydropyridines with benzyne

reactions of 1 ,zdihydropyridines (la-c) and 1,4-dihydropyridines (2a-c) in the presence of benzyne (3) under thermal conditions, and in the case of (2c) under photochemical conditions, have been investigated. benzyne acts as an oxidizing agent to convert dihydropyridine (la) and (2a) to the corresponding pyridine (4) or adds as a dienophile to (lb-c).

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Catalytic effect of green zinc oxide nanoparticles on multi –component reactions

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Catalytic effect of green zinc oxide nanoparticles on multi –component reactions

In this study, multi component Hantzsch reaction was carried out between various  Aromatic Aldehyde with Dimedone,Ethyl acetateand ammonium acetate to produce polyhydroquinolinederivatives under solvent-free conditions at 110oC by a (Zinc oxide  nanocatalyst) as effective Lewis acid. The remarkable advantages offered by this method compared with other methods are a green catalyst, simple work-u...

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ژورنال

عنوان ژورنال: YAKUGAKU ZASSHI

سال: 2015

ISSN: 0031-6903,1347-5231

DOI: 10.1248/yakushi.15-00203